LILY YANG

Extensive hands-on expertise in cell culture across human, mouse, and hamster lines, supporting both research and clinical trial pipelines.
Strong knowledge of GMP/GLP compliance, cell banking, and QC processes for high-quality cell production.
Skilled in automated cell culture platforms including Tecan Fluent and Integra Viaflo; proficient in culturing with Petri dishes, T-flasks, roller bottles, Erlenmeyer flasks, cell stacks, and multiwell plates.
Experienced in cell-based assays: ELISA, CELSIS, RT-PCR for mycoplasma detection, Western blotting, plasmid DNA sequencing, FBS qualification, IncuCyte imaging, and robotic systems.
Proven ability to implement structured cell tracking systems, SOPs, and inventory databases that improve data accessibility and traceability.

Established and managed Mammoth's centralized Cell Culture Core, supporting 18+ cell lines with >95% viability.
Built a traceable cell banking and tracking system via Benchling, from initial registration through production.
Designed and executed QC workflows for cell bank release (STR profiling, mycoplasma, sterility testing).
Delivered contamination-free cell plates and flasks to internal teams on-demand.
Conducted hands-on research experiments to validate and optimize parameters affecting cell growth (e.g. incubator type, cell dissociation methods)

Supported >110 in vivo pharmacology studies annually with delivery of high-viability tumor cell lines.
Created and maintained site-wide cell banks, including searchable documentation and CoAs.
Collaborated cross-functionally with research teams, ensuring availability, testing, and QC of requested cells.
Key contributor to study timelines and data integrity through proactive planning and responsiveness.

Expanded 150+ antibody-expressing cell lines; supported assay development and internal testing pipelines.
Authored QC reports and Certificates of Analysis for new cell banks.
Led cell culture onboarding for new hires and conducted internal cell health assays (CELSIS, RT-PCR).

Performed CAR-T cell manufacturing from primary blood samples using closed-system Miltenyi platforms.
Worked under cGMP conditions for aseptic processing, supporting clinical cell therapy development.

Maintained and distributed 70+ unique cell lines (e.g., HEK293, MDCK, Vero); supported internal R&D assays.
Served as a member of lab safety committee, contributing to EH&S compliance initiatives.

Led high-volume cell culture production for R&D and clinical trials.
Developed and implemented automated scheduling, inventory, and banking systems.
Trained and mentored junior staff; authored and maintained multiple SOPs.
Pioneered use of IncuCyte, robotic systems, and cell counters for assay optimization.