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Professional History

Dynamic research and development specialist with 15 years of experience guiding major organisations in therapeutic protein purification processes. Proven talent for establishing and enhancing laboratory procedures and processes, driving optimal efficiency and productivity for minimal cost. Innovative organisational leader, highly capable of coordinating research teams, vaccine production, and clinical trials. Excellent strategic planner with proven ability to direct large-scale biochemical projects with superior results.

Areas of Expertise

Research & Development •  Process Development & Optimization • Fermentation & Purification Process Design/Enhancement • Laboratory Management• Continuous Improvements • Product Improvement • Project Development • Team Building & Development • Strategic Planning & Scheduling • Research & Data Analysis •

Work experience

Jun 2014Present

Process Science Lead

GlaxoSmithKline plc Siena (Italy)

Direct 18 employees in materials, technology processes, and science laboratory management. Lead fermentation and purification process design, and devise improvements in protein and antigen production techniques. Determine resource needs, assess deviations and failures, and provide process solutions. Plan validation protocols, draft technical reports and experimental methods, and deliver technical support for internal manufacturing departments.

  • Increased organizational growth by 10 employees and lab activity by 50% through new process implementation and team organization.
  • Created model studies for process characterization and assessment.
  • Enhanced protein yield by 35% for Novartis vaccine adjuvant.
  • Improved production processes for meningococcal type B vaccine.
Dec 2001May 2014

Biotech Development & Manufacturing Researcher

Dompé SpA (Biotech Unit) L'Aquila (Italy)

Managed researchers, technicians, graduate students, laboratory equipment, and processes. Designed and improved laboratory and pilot-scale purification processes for recombinant proteins in E. coli. Completed biomass and supernatant recovery, and protein refolding. Ran batch production scheduling, and prepared records and documentation.

  • Devised purification process for nerve growth factor a recombinant protein used in neurotrophic keratitis and glaucoma treatment.
  • Improved fermentation process efficiency of rh-Annexin. Optimized product quality and yield by creating new scalable purification process.
  • Enhanced purification protocol for protein used in treatment of glioblastoma.

Completed cloning and development of fully human Fab fragment used in ovarian cancer treatment, and established purification process to improve affinity for receptor.

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PhD in Biochemistry

Degree in Biological Sciences

University of L’Aquilla, Italy

Professional Development/Workshops

Leading at the front line

Le GMP in Ricerca e Sviluppo

Basic requirements for Active Substances used as a Starting Material

A Global approach to Biopharma and Biotech separation and purification processes

Operator certification for pilot and process chromatography column packing

Language Fluencies

Italian & English

Computer Skills










MS Office (Word, Excel, Outlook)

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