Manager, Modeling Scientist, Drug Product Development
Bristol-Myers Squibb (Previously Celgene Corporation), Summit, NJ, USA
- Leveraged state-of-the-art crystal engineering techniques such as ADDICT and CSD python to address challenges in crystalline drug substance development
- Leveraged state-of-the-art thermodynamics modeling techniques such as PC-SAFT to optimize properties of amorphous drug substance developed through spray dried dispersion (SDD)
- Developed new methods to analyze particle morphology distribution (size and shape) characterized using static image analysis and related them to bulk powder properties such as powder flow
- Developed analysis pipelines for computational fluid dynamics models of drug development processes such as fluidized bed drying and mixing tanks
- Implemented data ingestion strategies for collecting data from materials profiling experiments and simulations into data lake to develop a digital twin of drug product development
- Developed mechanistic models and machine learning (ML) models for optimizing oral solid formulation development
